Sanibel Island Villas - Vacation Rentals in Route 66 Interpretive Center

Sycamore Hill Guesthouse From US $254
         

10.0 (10 Reviews)
House
  • Air Conditioner
  • Parking
  • Balcony/Terrace
Blue Door Farmhouse From US $239
         

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New
House
  • Air Conditioner
  • Parking
  • Pool
Hampton Inn & Suites Stroud From US $92
         

9.2 (1006 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pool
Adventure Acres Retreat From US $295
         

New
House
  • Air Conditioner
  • Parking
  • Pet Friendly
70-Acre Retreat with 2 Fishing Ponds Near Route 66 From US $184
         

Skyliner Motel From US $111
         

9.0 (2 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Bedding/Linens
70-Acre Retreat w/2 Fishing Ponds Near Route 66 From US $149
         

Hampton Inn & Suites Stroud From US $87
         

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8.8 (314 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pool
Cattle Country Lodge From US $118
         

8.0 (251 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • TV
Crazy Cow Farmhouse with Sweeping Country Views in Chandler, OK From US $158
         

10.0 (15 Reviews)
House
  • Air Conditioner
  • Pet Friendly
  • Security/Safety
The Tiny Home on Route 66 - Cozy 2 bed with WiFi From US $106
         

10.0 (15 Reviews)
House
  • Air Conditioner
  • Pet Friendly
  • Security/Safety
Route 66 Ranch with pool in charming Chandler. From US $295
         

10.0 (9 Reviews)
House
  • Air Conditioner
  • Parking
  • Pet Friendly
Modern Cabin on 20 private acres. just off Route 66. From US $253
         

10.0 (9 Reviews)
Cabin
  • Air Conditioner
  • Designated Smoking Area
  • TV
City Escape by ReTreat OKC From US $706
         

10.0 (1 Review)
House
  • Air Conditioner
  • Parking
  • Pool
Upstairs Apartment On Rout 66. 1 story above Historic Chandler, OK. From US $177
         

9.8 (23 Reviews)
Apartment
  • Air Conditioner
  • Parking
  • Pet Friendly
The USA Home - in Chandler, OK From US $190
         

9.8 (7 Reviews)
House
  • Air Conditioner
  • Pet Friendly
  • Security/Safety
Country Retreat north of Chandler From US $385
         

10.0 (1 Review)
Other
  • Air Conditioner
  • Parking
  • Pool
Private 40 Acre FARM, Log Cabin, Fishing & Fun From US $591
         

10.0 (5 Reviews)
Cabin
  • Air Conditioner
  • Parking
  • Designated Smoking Area
Chandler Vacation Rental on Route 66, Near Casino From US $137
         

Chandler House w/Fenced Backyard: Pets Welcome! From US $182
         

9.8 (8 Reviews)
House
  • Air Conditioner
  • Parking
  • Pet Friendly
Quaint 1 Bedroom Guesthouse just off of Route 66 From US $79
         

4.8 (5 Reviews)
Apartment
  • Air Conditioner
  • TV
  • Balcony/Terrace
Pro Tip: Sanibelislandvillas makes it easy to compare the best listings on Sanibelislandvillas homes from online vacation rental OTAs, including Booking.com and more. Use the Advanced Filter feature at the top to easily flip between Sanibelislandvillas homes, vacation rentals, bed and breakfasts, private Airbnb-style rentals availability, eco-friendly properties, property type, cancellation policies, prices, and several different options. All these make it easier to find the perfect accommodation for your next vacation in Route 66 Interpretive Center.

Weather in Route 66 Interpretive Center

View the weather forecast for Route 66 Interpretive Center before booking your Route 66 Interpretive Center Vacation Rentals to confirm your best time to go.

December - February
High 60°F       Low 26°F
March - May
High 77°F       Low 40°F
June - August
High 91°F       Low 64°F
September - November
High 84°F       Low 38°F

Route 66 Interpretive Center Vacation Rental Frequently Asked Questions

What are the top vacation rentals in Route 66 Interpretive Center?
How many vacation rentals are available in Route 66 Interpretive Center?

Currently, the total number of properties listed in 2026 is over 41 in the Route 66 Interpretive Center area, and still counting. By aggregating listings from multiple websites, offers an immense amount of choice of the best properties in Route 66 Interpretive Center.